Rap1 Can Bypass the FAK-Src-Paxillin Cascade to Induce Cell Spreading and Focal Adhesion Formation

We developed new image analysis tools to analyse quantitatively the extracellular-matrix-dependent cell spreading process imaged by live-cell epifluorescence microscopy. Using these tools, we investigated cell spreading induced by activation of the small GTPase, Rap1. After replating and initial adh...

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Detalles Bibliográficos
Autores principales: Ross, Sarah H., Spanjaard, Emma, Post, Anneke, Vliem, Marjolein J., Kristyanto, Hendy, Bos, Johannes L., de Rooij, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507925/
https://www.ncbi.nlm.nih.gov/pubmed/23209645
http://dx.doi.org/10.1371/journal.pone.0050072

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507925/
https://www.ncbi.nlm.nih.gov/pubmed/23209645
http://dx.doi.org/10.1371/journal.pone.0050072

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