Structural snapshots of the reaction coordinate for O-GlcNAc transferase

Visualization of the reaction coordinate undertaken by glycosyltransferases has remained elusive, but is critical for understanding this important class of enzyme. Using substrates and substrate mimics, we describe structural snapshots of all species along the kinetic pathway for human O-GlcNAc tran...

Descripción completa

Detalles Bibliográficos
Autores principales: Lazarus, Michael B., Jiang, Jiaoyang, Gloster, Tracey M., Zandberg, Wesley F., Whitworth, Garrett E., Vocadlo, David J., Walker, Suzanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3508357/
https://www.ncbi.nlm.nih.gov/pubmed/23103939
http://dx.doi.org/10.1038/nchembio.1109

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3508357/
https://www.ncbi.nlm.nih.gov/pubmed/23103939
http://dx.doi.org/10.1038/nchembio.1109

Ejemplares similares