Transcription activator-like effector hybrids for conditional control and rewiring of chromosomal transgene expression

The ability to conditionally rewire pathways in human cells holds great therapeutic potential. Transcription activator-like effectors (TALEs) are a class of naturally occurring specific DNA binding proteins that can be used to introduce targeted genome modifications or control gene expression. Here...

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Detalles Bibliográficos
Autores principales: Li, Yi, Moore, Richard, Guinn, Michael, Bleris, Leonidas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3508452/
https://www.ncbi.nlm.nih.gov/pubmed/23193439
http://dx.doi.org/10.1038/srep00897

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3508452/
https://www.ncbi.nlm.nih.gov/pubmed/23193439
http://dx.doi.org/10.1038/srep00897

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