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Transcription activator-like effector hybrids for conditional control and rewiring of chromosomal transgene expression
The ability to conditionally rewire pathways in human cells holds great therapeutic potential. Transcription activator-like effectors (TALEs) are a class of naturally occurring specific DNA binding proteins that can be used to introduce targeted genome modifications or control gene expression. Here...
Autores principales: | Li, Yi, Moore, Richard, Guinn, Michael, Bleris, Leonidas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3508452/ https://www.ncbi.nlm.nih.gov/pubmed/23193439 http://dx.doi.org/10.1038/srep00897 |
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