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Novel Conformation of an RNA Structural Switch
[Image: see text] The RNA duplex, (5′GACGAGUGUCA)(2), has two conformations in equilibrium. The nuclear magnetic resonance solution structure reveals that the major conformation of the loop, 5′GAGU/3′UGAG, is novel and contains two unusual Watson–Crick/Hoogsteen GG pairs with G residues in the syn c...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3508625/ https://www.ncbi.nlm.nih.gov/pubmed/23134175 http://dx.doi.org/10.1021/bi301372t |