Cargando…
Novel Conformation of an RNA Structural Switch
[Image: see text] The RNA duplex, (5′GACGAGUGUCA)(2), has two conformations in equilibrium. The nuclear magnetic resonance solution structure reveals that the major conformation of the loop, 5′GAGU/3′UGAG, is novel and contains two unusual Watson–Crick/Hoogsteen GG pairs with G residues in the syn c...
Autores principales: | Kennedy, Scott D., Kierzek, Ryszard, Turner, Douglas H. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2012
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3508625/ https://www.ncbi.nlm.nih.gov/pubmed/23134175 http://dx.doi.org/10.1021/bi301372t |
Ejemplares similares
-
Molecular dynamics correctly models the unusual major conformation of the GAGU RNA internal loop and with NMR reveals an unusual minor conformation
por: Spasic, Aleksandar, et al.
Publicado: (2018) -
RNA Internal Loops with Tandem AG Pairs: The Structure of the 5′GAGU/3′UGAG Loop Can Be Dramatically Different from Others, Including 5′AAGU/3′UGAA
por: Hammond, Nicholas B., et al.
Publicado: (2010) -
The 3′ Splice Site of Influenza A Segment 7 mRNA Can Exist in Two Conformations: A Pseudoknot and a Hairpin
por: Moss, Walter N., et al.
Publicado: (2012) -
Microarrays for identifying binding sites and probing structure of RNAs
por: Kierzek, Ryszard, et al.
Publicado: (2015) -
Correction: The 3′ Splice Site of Influenza A Segment 7 mRNA Can Exist in Two Conformations: A Pseudoknot and a Hairpin
por: Moss, Walter N., et al.
Publicado: (2012)