A plasma membrane-targeted cytosolic domain of STIM1 selectively activates ARC channels, an arachidonate-regulated store-independent Orai channel

The Orai family of calcium channels includes the store-operated CRAC channels and store-independent, arachidonic acid (AA)-regulated ARC channels. Both depend on STIM1 for their activation but, whereas CRAC channel activation involves sensing the depletion of intracellular calcium stores via a lumin...

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Detalles Bibliográficos
Autores principales: Thompson, Jill L., Shuttleworth, Trevor J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Technical Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3508776/
https://www.ncbi.nlm.nih.gov/pubmed/22992514
http://dx.doi.org/10.4161/chan.21947

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3508776/
https://www.ncbi.nlm.nih.gov/pubmed/22992514
http://dx.doi.org/10.4161/chan.21947

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