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Phosphorylation of the rat Ins(1,4,5)P(3) receptor at T930 within the coupling domain decreases its affinity to Ins(1,4,5)P(3)
The Ins(1,4,5)P(3) receptor acts as a central hub for Ca(2+) signaling by integrating multiple signaling modalities into Ca(2+) release from intracellular stores downstream of G-protein and tyrosine kinase-coupled receptor stimulation. As such, the Ins(1,4,5)P(3) receptor plays fundamental roles in...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Landes Bioscience
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3508777/ https://www.ncbi.nlm.nih.gov/pubmed/22878752 http://dx.doi.org/10.4161/chan.21170 |