Different designs of kinase-phosphatase interactions and phosphatase sequestration shapes the robustness and signal flow in the MAPK cascade

BACKGROUND: The three layer mitogen activated protein kinase (MAPK) signaling cascade exhibits different designs of interactions between its kinases and phosphatases. While the sequential interactions between the three kinases of the cascade are tightly preserved, the phosphatases of the cascade, su...

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Detalles Bibliográficos
Autores principales: Sarma, Uddipan, Ghosh, Indira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3508828/
https://www.ncbi.nlm.nih.gov/pubmed/22748295
http://dx.doi.org/10.1186/1752-0509-6-82

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3508828/
https://www.ncbi.nlm.nih.gov/pubmed/22748295
http://dx.doi.org/10.1186/1752-0509-6-82

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