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Glucose Metabolic Trapping in Mouse Arteries: Nonradioactive Assay of Atherosclerotic Plaque Inflammation Applicable to Drug Discovery

BACKGROUND: (18)F-Fluorodeoxyglucose (FDG)-positron emission tomography (PET) imaging of atherosclerosis in the clinic is based on preferential accumulation of radioactive glucose analog in atherosclerotic plaques. FDG-PET is challenging in mouse models due to limited resolution and high cost. We ai...

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Detalles Bibliográficos
Autores principales: Conway, Richard G., Chernet, Eyassu, De Rosa, David C., Benschop, Robert J., Need, Anne B., Collins, Emily C., Bean, James S., Kalbfleisch, J. Michael, Rekhter, Mark D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3508896/
https://www.ncbi.nlm.nih.gov/pubmed/23209718
http://dx.doi.org/10.1371/journal.pone.0050349