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Glutamine Treatment Attenuates Endoplasmic Reticulum Stress and Apoptosis in TNBS-Induced Colitis

Endoplasmic reticulum (ER) stress and apoptotic cell death play an important role in the pathogenesis and perpetuation of inflammatory bowel disease (IBD). We aimed to explore the potential of glutamine to reduce ER stress and apoptosis in a rat model of experimental IBD. Colitis was induced in male...

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Detalles Bibliográficos
Autores principales: Crespo, Irene, San-Miguel, Beatriz, Prause, Carolina, Marroni, Norma, Cuevas, María J., González-Gallego, Javier, Tuñón, María J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3508929/
https://www.ncbi.nlm.nih.gov/pubmed/23209735
http://dx.doi.org/10.1371/journal.pone.0050407