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Molecular evolution of a-kinase anchoring protein (AKAP)-7: implications in comparative PKA compartmentalization
BACKGROUND: A-Kinase Anchoring Proteins (AKAPs) are molecular scaffolding proteins mediating the assembly of multi-protein complexes containing cAMP-dependent protein kinase A (PKA), directing the kinase in discrete subcellular locations. Splice variants from the AKAP7 gene (AKAP15/18) are vital com...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3508976/ https://www.ncbi.nlm.nih.gov/pubmed/22834419 http://dx.doi.org/10.1186/1471-2148-12-125 |