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Molecular evolution of a-kinase anchoring protein (AKAP)-7: implications in comparative PKA compartmentalization

BACKGROUND: A-Kinase Anchoring Proteins (AKAPs) are molecular scaffolding proteins mediating the assembly of multi-protein complexes containing cAMP-dependent protein kinase A (PKA), directing the kinase in discrete subcellular locations. Splice variants from the AKAP7 gene (AKAP15/18) are vital com...

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Detalles Bibliográficos
Autores principales: Johnson, Keven R, Nicodemus-Johnson, Jessie, Carnegie, Graeme K, Danziger, Robert S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3508976/
https://www.ncbi.nlm.nih.gov/pubmed/22834419
http://dx.doi.org/10.1186/1471-2148-12-125