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Hepatocyte Growth Factor Increases Vascular Endothelial Growth Factor-A Production in Human Synovial Fibroblasts through c-Met Receptor Pathway

BACKGROUND: Angiogenesis is essential for the progression of osteoarthritis (OA). Hepatocyte growth factor (HGF) is an angiogenic mediator, and it shows elevated levels in regions of OA. However, the relationship between HGF and vascular endothelial growth factor (VEGF-A) in OA synovial fibroblasts...

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Detalles Bibliográficos
Autores principales: Lin, Yu-Min, Huang, Yuan-Li, Fong, Yi-Chin, Tsai, Chun-Hao, Chou, Ming-Chih, Tang, Chih-Hsin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3508989/
https://www.ncbi.nlm.nih.gov/pubmed/23209838
http://dx.doi.org/10.1371/journal.pone.0050924