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Transient defects of mitotic spindle geometry and chromosome segregation errors

Assembly of a bipolar mitotic spindle is essential to ensure accurate chromosome segregation and prevent aneuploidy, and severe mitotic spindle defects are typically associated with cell death. Recent studies have shown that mitotic spindles with initial geometric defects can undergo specific rearra...

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Detalles Bibliográficos
Autores principales: Silkworth, William T, Cimini, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3509025/
https://www.ncbi.nlm.nih.gov/pubmed/22883214
http://dx.doi.org/10.1186/1747-1028-7-19