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Progesterone Acts via the Nuclear Glucocorticoid Receptor to Suppress IL-1β-Induced COX-2 Expression in Human Term Myometrial Cells

Progesterone is widely used to prolong gestation in women at risk of preterm labour (PTL), and acts at least in part via the inhibition of inflammatory cytokine-induced prostaglandin synthesis. This study investigates the mechanisms responsible for this inhibition in human myometrial cells. We used...

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Detalles Bibliográficos
Autores principales: Lei, Kaiyu, Chen, Li, Georgiou, Ektoras X., Sooranna, Suren R., Khanjani, Shirin, Brosens, Jan J., Bennett, Phillip R., Johnson, Mark R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3509141/
https://www.ncbi.nlm.nih.gov/pubmed/23209664
http://dx.doi.org/10.1371/journal.pone.0050167