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Polyacetylene Compound from Cirsium japonicum var. ussuriense Inhibited Caspase-1-mediated IL-1β Expression

Our previous report showed that polyacetylene compound, 1-Heptadecene-11, 13-diyne-8, 9, 10-triol (PA) from the root of Cirsium japonicum var. ussuriense has anti-inflammatory activity. In this study we investigated the role of the PA as inhibitor of caspase-1, which converts prointerleukin-1β (proI...

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Detalles Bibliográficos
Autores principales: Shim, Hong, Moon, Jung Sun, Lee, Sookyeon, Yim, Dongsool, Kang, Tae Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association of Immunologists 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3509166/
https://www.ncbi.nlm.nih.gov/pubmed/23213315
http://dx.doi.org/10.4110/in.2012.12.5.213