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IL-17-deficient allogeneic bone marrow transplantation prevents the induction of collagen-induced arthritis in DBA/1J mice

IL-17-producing CD4(+) T cells (Th17) play important functions in autoimmune diseases and allograft rejection of solid organs. We examined the effects of IL 17 and its mechanism of action on arthritis in a murine collagen-induced arthritis (CIA) model using bone marrow transplantation (BMT) system....

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Detalles Bibliográficos
Autores principales: Park, Min-Jung, Park, Hyun-Sil, Oh, Hye-Joa, Lim, Jung-Yeon, Yoon, Bo-Young, Kim, Ho-Youn, Cho, Mi-La, Cho, Seok-Goo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3509186/
https://www.ncbi.nlm.nih.gov/pubmed/23114425
http://dx.doi.org/10.3858/emm.2012.44.11.078