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Fluorescent and photo-oxidizing TimeSTAMP tags track protein fates in light and electron microscopy

Protein synthesis is highly regulated throughout nervous system development, plasticity, and regeneration. However, tracking the distributions of specific new protein species has not been possible in living neurons or at the ultrastructural level. Previously we created TimeSTAMP epitope tags, drug-c...

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Detalles Bibliográficos
Autores principales: Butko, Margaret T., Yang, Jin, Geng, Yang, Kim, Hyung Joon, Jeon, Noo Li, Shu, Xiaokun, Mackey, Mason R., Ellisman, Mark H., Tsien, Roger Y., Lin, Michael Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3509268/
https://www.ncbi.nlm.nih.gov/pubmed/23103964
http://dx.doi.org/10.1038/nn.3246