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Immunotherapies: The Blockade of Inhibitory Signals

T lymphocytes require signaling by the T cell receptor and by nonclonotypic cosignaling receptors. The costimulatory and inhibitory signals profoundly influence the course of immune responses by amplifying or reducing the transcriptional effects of T cell receptor triggering. The inhibitory receptor...

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Detalles Bibliográficos
Autores principales: Wu, Yan-Ling, Liang, Jing, Zhang, Wen, Tanaka, Yoshimasa, Sugiyama, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3509335/
https://www.ncbi.nlm.nih.gov/pubmed/23197939
http://dx.doi.org/10.7150/ijbs.5273