Network rewiring is an important mechanism of gene essentiality change

Gene essentiality changes are crucial for organismal evolution. However, it is unclear how essentiality of orthologs varies across species. We investigated the underlying mechanism of gene essentiality changes between yeast and mouse based on the framework of network evolution and comparative genomi...

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Detalles Bibliográficos
Autores principales: Kim, Jinho, Kim, Inhae, Han, Seong Kyu, Bowie, James U., Kim, Sanguk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3509348/
https://www.ncbi.nlm.nih.gov/pubmed/23198090
http://dx.doi.org/10.1038/srep00900

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3509348/
https://www.ncbi.nlm.nih.gov/pubmed/23198090
http://dx.doi.org/10.1038/srep00900

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