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Network rewiring is an important mechanism of gene essentiality change
Gene essentiality changes are crucial for organismal evolution. However, it is unclear how essentiality of orthologs varies across species. We investigated the underlying mechanism of gene essentiality changes between yeast and mouse based on the framework of network evolution and comparative genomi...
Autores principales: | Kim, Jinho, Kim, Inhae, Han, Seong Kyu, Bowie, James U., Kim, Sanguk |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3509348/ https://www.ncbi.nlm.nih.gov/pubmed/23198090 http://dx.doi.org/10.1038/srep00900 |
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