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The Average IFN-γ Secreting Capacity of Specific CD8(+) T Cells Is Compromised While Increasing Copies of a Single T Cell Epitope Encoded by DNA Vaccine
Previous studies suggested that both the frequency and the mean fluorescence intensity (MFI) of cytokine secreting T cells could be of great value for immunogenicity evaluation of a vaccine. In this study, by constructing epitope-based DNA vaccines encoding a previously identified CD8(+) T cell epit...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3509377/ https://www.ncbi.nlm.nih.gov/pubmed/23251217 http://dx.doi.org/10.1155/2012/478052 |