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Rab27a Targeting to Melanosomes Requires Nucleotide Exchange but Not Effector Binding
Rab GTPases are important determinants of organelle identity and regulators of vesicular transport pathways. Consequently, each Rab occupies a highly specific subcellular localization. However, the precise mechanisms governing Rab targeting remain unclear. Guanine nucleotide exchange factors (GEFs),...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3509405/ https://www.ncbi.nlm.nih.gov/pubmed/21554507 http://dx.doi.org/10.1111/j.1600-0854.2011.01216.x |