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TLX controls angiogenesis through interaction with the von Hippel-Lindau protein

TLX is known as the orphan nuclear receptor indispensable for maintaining neural stem cells in adult neurogenesis. We report here that neuroblastoma cell lines express high levels of TLX, which further increase in hypoxia to enhance the angiogenic capacity of these cells. The proangiogenetic activit...

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Detalles Bibliográficos
Autores principales: Zeng, Zhao-jun, Johansson, Erik, Hayashi, Amiko, Chavali, Pavithra L., Akrap, Nina, Yoshida, Takeshi, Kohno, Kimitoshi, Izumi, Hiroto, Funa, Keiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3509445/
https://www.ncbi.nlm.nih.gov/pubmed/23213445
http://dx.doi.org/10.1242/bio.2012893