Targeting developmental regulators of zebrafish exocrine pancreas as a therapeutic approach in human pancreatic cancer

Histone deacetylases (HDACs) and RNA polymerase III (POLR3) play vital roles in fundamental cellular processes, and deregulation of these enzymes has been implicated in malignant transformation. Hdacs and Polr3 are required for exocrine pancreatic epithelial proliferation during morphogenesis in zeb...

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Detalles Bibliográficos
Autores principales: Yee, Nelson S., Zhou, Weiqiang, Chun, Stephen G., Liang, I-Chau, Yee, Rosemary K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3509454/
https://www.ncbi.nlm.nih.gov/pubmed/23213420
http://dx.doi.org/10.1242/bio.2012539

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3509454/
https://www.ncbi.nlm.nih.gov/pubmed/23213420
http://dx.doi.org/10.1242/bio.2012539

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