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The Effect of Glycyrrhetinic Acid on Pharmacokinetics of Cortisone and Its Metabolite Cortisol in Rats

The purpose of this paper is to study pharmacokinetics of cortisone (E) and its metabolite cortisol (F) in rats after administration of glycyrrhetinic acid (GA) and cortisone. Healthy male SD rats were randomized to be given 20 mg/kg E or E combined with 10 mg/kg GA. Blood samples were collected at...

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Detalles Bibliográficos
Autores principales: Lin, Dan, Sun, Wei, Wang, Zhe, Chen, Lian-Guo, Chen, Xiao-Le, Wang, Shuang-Hu, Li, Wan-Shu, Ge, Ren-Shan, Hu, Guo-Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3509542/
https://www.ncbi.nlm.nih.gov/pubmed/23258958
http://dx.doi.org/10.1155/2012/856324