Molecular Mechanisms of Pharmaceutical Drug Binding into Calsequestrin

Calsequestrin (CASQ) is a major Ca(2+)-storage/buffer protein present in the sarcoplasmic reticulum of both skeletal (CASQ1) and cardiac (CASQ2) muscles. CASQ has significant affinity for a number of pharmaceutical drugs with known muscular toxicities. Our approach, with in silico molecular docking,...

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Detalles Bibliográficos
Autores principales: Subra, Arun K., Nissen, Mark S., Lewis, Kevin M., Muralidharan, Ashwin K., Sanchez, Emiliano J., Milting, Hendrik, Kang, ChulHee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3509583/
https://www.ncbi.nlm.nih.gov/pubmed/23203067
http://dx.doi.org/10.3390/ijms131114326

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3509583/
https://www.ncbi.nlm.nih.gov/pubmed/23203067
http://dx.doi.org/10.3390/ijms131114326

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