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Alzheimer’s Disease-Associated Neurotoxic Peptide Amyloid-β Impairs Base Excision Repair in Human Neuroblastoma Cells

Alzheimer’s disease (AD) is the leading cause of dementia in developed countries. It is characterized by two major pathological hallmarks, one of which is the extracellular aggregation of the neurotoxic peptide amyloid-β (Aβ), which is known to generate oxidative stress. In this study, we showed tha...

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Detalles Bibliográficos
Autores principales: Forestier, Anne, Douki, Thierry, Sauvaigo, Sylvie, De Rosa, Viviana, Demeilliers, Christine, Rachidi, Walid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3509609/
https://www.ncbi.nlm.nih.gov/pubmed/23203093
http://dx.doi.org/10.3390/ijms131114766