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A DNA Repair BRCA1 Estrogen Receptor and Targeted Therapy in Breast Cancer

BRCA1 is a key mediator of DNA repair pathways and participates in the maintenance of the genomic integrity of cells. The control of DNA damage repair mechanisms by BRCA1 is of great interest since molecular defects in this pathway may reflect a predictive value in terms of a cell’s sensitivity to D...

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Detalles Bibliográficos
Autor principal: Ratanaphan, Adisorn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3509617/
https://www.ncbi.nlm.nih.gov/pubmed/23203101
http://dx.doi.org/10.3390/ijms131114898