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Arenaviruses and Lethal Mutagenesis. Prospects for New Ribavirin-based Interventions

Lymphocytic choriomeningitis virus (LCMV) has contributed to unveil some of the molecular mechanisms of lethal mutagenesis, or loss of virus infectivity due to increased mutation rates. Here we review these developments, and provide additional evidence that ribavirin displays a dual mutagenic and in...

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Detalles Bibliográficos
Autores principales: Moreno, Héctor, Grande-Pérez, Ana, Domingo, Esteban, Martín, Verónica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3509673/
https://www.ncbi.nlm.nih.gov/pubmed/23202505
http://dx.doi.org/10.3390/v4112786