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A nuclear Argonaute promotes multi-generational epigenetic inheritance and germline immortality

Epigenetic information is frequently erased near the start of each new generation (1). In some cases, however, epigenetic information can be transmitted from parent to progeny (epigenetic inheritance) (2). A particularly striking example of epigenetic inheritance is dsRNA-mediated gene silencing (RN...

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Detalles Bibliográficos
Autores principales: Buckley, Bethany, Burkhart, Kirk, Gu, Sam Guoping, Spracklin, George, Kershner, Aaron, Fritz, Heidi, Kimble, Judith, Fire, Andrew, Kennedy, Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3509936/
https://www.ncbi.nlm.nih.gov/pubmed/22810588
http://dx.doi.org/10.1038/nature11352