Increasing the oral bioavailability of poorly water-soluble carbamazepine using immediate-release pellets supported on SBA-15 mesoporous silica

BACKGROUND AND METHODS: The aim of this study was to develop an immediate-release pellet formulation with improved drug dissolution and adsorption. Carbamazepine, a poorly water-soluble drug, was adsorbed into mesoporous silica (SBA-15-CBZ) via a wetness impregnation method and then processed by ext...

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Detalles Bibliográficos
Autores principales: Wang, Zhouhua, Chen, Bao, Quan, Guilan, Li, Feng, Wu, Qiaoli, Dian, Linghui, Dong, Yixuan, Li, Ge, Wu, Chuanbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3509994/
https://www.ncbi.nlm.nih.gov/pubmed/23209366
http://dx.doi.org/10.2147/IJN.S37650

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3509994/
https://www.ncbi.nlm.nih.gov/pubmed/23209366
http://dx.doi.org/10.2147/IJN.S37650

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