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The kinesin-14 Klp2 is negatively regulated by the SIN for proper spindle elongation and telophase nuclear positioning

In Schizosaccharomyces pombe, a late mitotic kinase pathway called the septation initiation network (SIN) triggers cytokinesis. Here we show that the SIN is also involved in regulating anaphase spindle elongation and telophase nuclear positioning via inhibition of Klp2, a minus end–directed kinesin-...

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Detalles Bibliográficos
Autores principales: Mana-Capelli, Sebastian, McLean, Janel R., Chen, Chun-Ti, Gould, Kathleen L., McCollum, Dannel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510020/
https://www.ncbi.nlm.nih.gov/pubmed/23087209
http://dx.doi.org/10.1091/mbc.E12-07-0532