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Gαs promotes EEA1 endosome maturation and shuts down proliferative signaling through interaction with GIV (Girdin)

The organization of the endocytic system into biochemically distinct subcompartments allows for spatial and temporal control of the strength and duration of signaling. Recent work has established that Akt cell survival signaling via the epidermal growth factor receptor (EGFR) occurs from APPL early...

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Detalles Bibliográficos
Autores principales: Beas, Anthony O., Taupin, Vanessa, Teodorof, Carmen, Nguyen, Lien T., Garcia-Marcos, Mikel, Farquhar, Marilyn G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510023/
https://www.ncbi.nlm.nih.gov/pubmed/23051738
http://dx.doi.org/10.1091/mbc.E12-02-0133