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Selective Pressure Causes an RNA Virus to Trade Reproductive Fitness for Increased Structural and Thermal Stability of a Viral Enzyme

The modulation of fitness by single mutational substitutions during environmental change is the most fundamental consequence of natural selection. The antagonistic tradeoffs of pleiotropic mutations that can be selected under changing environments therefore lie at the foundation of evolutionary biol...

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Detalles Bibliográficos
Autores principales: Dessau, Moshe, Goldhill, Daniel, McBride, Robert L., Turner, Paul E., Modis, Yorgo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510033/
https://www.ncbi.nlm.nih.gov/pubmed/23209446
http://dx.doi.org/10.1371/journal.pgen.1003102