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Deubiquitylation Machinery Is Required for Embryonic Polarity in Caenorhabditis elegans

The Caenorhabditis elegans one-cell embryo polarizes in response to a cue from the paternally donated centrosome and asymmetrically segregates cell fate determinants that direct the developmental program of the worm. We have found that genes encoding putative deubiquitylating enzymes (DUBs) are requ...

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Detalles Bibliográficos
Autores principales: McCloskey, Richard J., Kemphues, Kenneth J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510043/
https://www.ncbi.nlm.nih.gov/pubmed/23209443
http://dx.doi.org/10.1371/journal.pgen.1003092