Population-Based Resequencing of APOA1 in 10,330 Individuals: Spectrum of Genetic Variation, Phenotype, and Comparison with Extreme Phenotype Approach

Rare genetic variants, identified by in-detail resequencing of loci, may contribute to complex traits. We used the apolipoprotein A-I gene (APOA1), a major high-density lipoprotein (HDL) gene, and population-based resequencing to determine the spectrum of genetic variants, the phenotypic characteris...

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Detalles Bibliográficos
Autores principales: Haase, Christiane L., Frikke-Schmidt, Ruth, Nordestgaard, Børge G., Tybjærg-Hansen, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510059/
https://www.ncbi.nlm.nih.gov/pubmed/23209431
http://dx.doi.org/10.1371/journal.pgen.1003063

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510059/
https://www.ncbi.nlm.nih.gov/pubmed/23209431
http://dx.doi.org/10.1371/journal.pgen.1003063

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