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Accurate Prediction of the Dynamical Changes within the Second PDZ Domain of PTP1e

Experimental NMR relaxation studies have shown that peptide binding induces dynamical changes at the side-chain level throughout the second PDZ domain of PTP1e, identifying as such the collection of residues involved in long-range communication. Even though different computational approaches have id...

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Detalles Bibliográficos
Autores principales: Cilia, Elisa, Vuister, Geerten W., Lenaerts, Tom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510070/
https://www.ncbi.nlm.nih.gov/pubmed/23209399
http://dx.doi.org/10.1371/journal.pcbi.1002794