Identification of Compounds with Anti-Proliferative Activity against Trypanosoma brucei brucei Strain 427 by a Whole Cell Viability Based HTS Campaign

Human African Trypanosomiasis (HAT) is caused by two trypanosome sub-species, Trypanosoma brucei rhodesiense and Trypanosoma brucei gambiense. Drugs available for the treatment of HAT have significant issues related to difficult administration regimes and limited efficacy across species and disease...

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Detalles Bibliográficos
Autores principales: Sykes, Melissa L., Baell, Jonathan B., Kaiser, Marcel, Chatelain, Eric, Moawad, Sarah R., Ganame, Danny, Ioset, Jean-Robert, Avery, Vicky M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510080/
https://www.ncbi.nlm.nih.gov/pubmed/23209849
http://dx.doi.org/10.1371/journal.pntd.0001896

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510080/
https://www.ncbi.nlm.nih.gov/pubmed/23209849
http://dx.doi.org/10.1371/journal.pntd.0001896

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