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The Ortholog Conjecture Is Untestable by the Current Gene Ontology but Is Supported by RNA Sequencing Data

The ortholog conjecture posits that orthologous genes are functionally more similar than paralogous genes. This conjecture is a cornerstone of phylogenomics and is used daily by both computational and experimental biologists in predicting, interpreting, and understanding gene functions. A recent stu...

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Detalles Bibliográficos
Autores principales: Chen, Xiaoshu, Zhang, Jianzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510086/
https://www.ncbi.nlm.nih.gov/pubmed/23209392
http://dx.doi.org/10.1371/journal.pcbi.1002784