Saikosaponin a Mediates the Anticonvulsant Properties in the HNC Models of AE and SE by Inhibiting NMDA Receptor Current and Persistent Sodium Current

Epilepsy is one of the most common neurological disorders, yet its treatment remains unsatisfactory. Saikosaponin a (SSa), a triterpene saponin derived from Bupleurum chinensis DC., has been demonstrated to have significant antiepileptic activity in a variety of epilepsy models in vivo. However, the...

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Detalles Bibliográficos
Autores principales: Yu, Yun-Hong, Xie, Wei, Bao, Yong, Li, Hui-Ming, Hu, San-Jue, Xing, Jun-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510157/
https://www.ncbi.nlm.nih.gov/pubmed/23209812
http://dx.doi.org/10.1371/journal.pone.0050694

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510157/
https://www.ncbi.nlm.nih.gov/pubmed/23209812
http://dx.doi.org/10.1371/journal.pone.0050694

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