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Modeling Truncated AR Expression in a Natural Androgen Responsive Environment and Identification of RHOB as a Direct Transcriptional Target
Recent studies identifying putative truncated androgen receptor isoforms with ligand-independent activity have shed new light on the acquisition of androgen depletion independent (ADI) growth of prostate cancer. In this study, we present a model system in which a C-terminally truncated variant of an...
Autores principales: | Tsai, Hui-Chi, Boucher, David L., Martinez, Anthony, Tepper, Clifford G., Kung, Hsing-Jien |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510170/ https://www.ncbi.nlm.nih.gov/pubmed/23209612 http://dx.doi.org/10.1371/journal.pone.0049887 |
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