Modeling Truncated AR Expression in a Natural Androgen Responsive Environment and Identification of RHOB as a Direct Transcriptional Target

Recent studies identifying putative truncated androgen receptor isoforms with ligand-independent activity have shed new light on the acquisition of androgen depletion independent (ADI) growth of prostate cancer. In this study, we present a model system in which a C-terminally truncated variant of an...

Descripción completa

Detalles Bibliográficos
Autores principales: Tsai, Hui-Chi, Boucher, David L., Martinez, Anthony, Tepper, Clifford G., Kung, Hsing-Jien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510170/
https://www.ncbi.nlm.nih.gov/pubmed/23209612
http://dx.doi.org/10.1371/journal.pone.0049887

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510170/
https://www.ncbi.nlm.nih.gov/pubmed/23209612
http://dx.doi.org/10.1371/journal.pone.0049887

Ejemplares similares