Differential Functions of C- and N-Terminal Hepatitis B x Protein in Liver Cells Treated with Doxorubicin in Normoxic or Hypoxic Condition

Hepatitis viral B x protein (HBx), a hepatocarcinogen, is frequently mutated. Hypoxia influences the growth of HCC and also the sensitivity of tumor cells to treatments. We aimed to test the role of HBx and acute hypoxia in the efficacy of chemotherapy. In this study, we established 4 Chang liver ce...

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Detalles Bibliográficos
Autores principales: Chau, Davor Kin-fan, Chen, George Gong, Zhang, Haitao, Leung, Billy Cheuk Sing, Chun, Sukying, Lai, Paul Bo-san
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510201/
https://www.ncbi.nlm.nih.gov/pubmed/23209654
http://dx.doi.org/10.1371/journal.pone.0050118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510201/
https://www.ncbi.nlm.nih.gov/pubmed/23209654
http://dx.doi.org/10.1371/journal.pone.0050118

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