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Differential Functions of C- and N-Terminal Hepatitis B x Protein in Liver Cells Treated with Doxorubicin in Normoxic or Hypoxic Condition
Hepatitis viral B x protein (HBx), a hepatocarcinogen, is frequently mutated. Hypoxia influences the growth of HCC and also the sensitivity of tumor cells to treatments. We aimed to test the role of HBx and acute hypoxia in the efficacy of chemotherapy. In this study, we established 4 Chang liver ce...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510201/ https://www.ncbi.nlm.nih.gov/pubmed/23209654 http://dx.doi.org/10.1371/journal.pone.0050118 |