Allopregnanolone Reinstates Tyrosine Hydroxylase Immunoreactive Neurons and Motor Performance in an MPTP-Lesioned Mouse Model of Parkinson's Disease

Restorative/protective therapies to restore dopamine neurons in the substantia nigra pars compacta (SNpc) are greatly needed to effectively change the debilitating course of Parkinson's disease. In this study, we tested the therapeutic potential of a neurogenic neurosteroid, allopregnanolone, i...

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Detalles Bibliográficos
Autores principales: Adeosun, Samuel O., Hou, Xu, Jiao, Yun, Zheng, Baoying, Henry, Sherry, Hill, Rosanne, He, Zhi, Pani, Amar, Kyle, Patrick, Ou, Xiaoming, Mosley, Thomas, Farley, Jerry M., Stockmeier, Craig, Paul, Ian, Bigler, Steven, Brinton, Roberta Diaz, Smeyne, Richard, Wang, Jun Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510204/
https://www.ncbi.nlm.nih.gov/pubmed/23209637
http://dx.doi.org/10.1371/journal.pone.0050040

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510204/
https://www.ncbi.nlm.nih.gov/pubmed/23209637
http://dx.doi.org/10.1371/journal.pone.0050040

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