Molecular Modeling Study on Tunnel Behavior in Different Histone Deacetylase Isoforms

Histone deacetylases (HDACs) have emerged as effective therapeutic targets in the treatment of various diseases including cancers as these enzymes directly involved in the epigenetic regulation of genes. However the development of isoform-selective HDAC inhibitors has been a challenge till date sinc...

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Detalles Bibliográficos
Autores principales: Thangapandian, Sundarapandian, John, Shalini, Lee, Yuno, Arulalapperumal, Venkatesh, Lee, Keun Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510210/
https://www.ncbi.nlm.nih.gov/pubmed/23209570
http://dx.doi.org/10.1371/journal.pone.0049327

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510210/
https://www.ncbi.nlm.nih.gov/pubmed/23209570
http://dx.doi.org/10.1371/journal.pone.0049327

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