Prevalence and Clinical Course in Invasive Infections with Meningococcal Endotoxin Variants

BACKGROUND: Meningococci produce a penta-acylated instead of hexa-acylated lipid A when their lpxL1 gene is inactivated. Meningococcal strains with such lipid A endotoxin variants have been found previously in adult meningitis patients, where they caused less blood coagulopathy because of decreased...

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Detalles Bibliográficos
Autores principales: Rodenburg, Gerwin D., Fransen, Floris, Bogaert, Debby, Schipper, Kim, Groenwold, Rolf H. H., Hamstra, Hendrik Jan, Westerhuis, Brenda M., van de Beek, Diederik, van der Ley, Peter, Sanders, Elisabeth A. M., van der Ende, Arie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510230/
https://www.ncbi.nlm.nih.gov/pubmed/23209568
http://dx.doi.org/10.1371/journal.pone.0049295

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510230/
https://www.ncbi.nlm.nih.gov/pubmed/23209568
http://dx.doi.org/10.1371/journal.pone.0049295

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