Dual Inhibition of PI3K/Akt/mTOR Pathway and Role of Autophagy in Non-Small Cell Lung Cancer Cells

BACKGROUND: The phosphoinositide 3-kinase (PI3K)/Akt/mammalian target of rapamycin (mTOR) signaling axis has emerged as a novel target for cancer therapy. Agents that inhibit this pathway are currently under development for lung cancer treatment. In the present study, we have tested whether dual inh...

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Detalles Bibliográficos
Autores principales: Jeong, Eun-Hui, Choi, Hyeong Sim, Lee, Tae-Gul, Kim, Hye-Ryoun, Kim, Cheol Hyeon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Academy of Tuberculosis and Respiratory Diseases 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510285/
https://www.ncbi.nlm.nih.gov/pubmed/23227075
http://dx.doi.org/10.4046/trd.2012.72.4.343

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510285/
https://www.ncbi.nlm.nih.gov/pubmed/23227075
http://dx.doi.org/10.4046/trd.2012.72.4.343

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