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Lack of MMP10 exacerbates experimental colitis and promotes development of inflammation-associated colonic dysplasia

Inflammatory bowel diseases such as ulcerative colitis represent serious health burdens, both because of the tissue-damaging disease itself, and because of an elevated risk of colon cancer. The increased expression of many members of the matrix metalloproteinase (MMP) family of enzymes that occurs i...

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Detalles Bibliográficos
Autores principales: Koller, Felicitas L., Dozier, E. Ashley, Nam, Ki Taek, Swee, Mei, Birkland, Timothy P., Parks, William C., Fingleton, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510327/
https://www.ncbi.nlm.nih.gov/pubmed/23044923
http://dx.doi.org/10.1038/labinvest.2012.141